The European Researchers’ Night celebrating research, innovation and science, organized in Cyprus by the Research and Innovation Foundation since 2006, will take place on September 24^th, 2021. Ιn the framework of the event entitled ENGAGE – European researchers’ Night in Cyprus: the diGitAl and Green agE, scientists, academics, researchers and entrepreneurs will present their activities and achievements to the public. For the purposes of the event, the RIF announces an open Call for the submission of Expressions of Interest by entities of the Research and Innovation (R&I) ecosystem, giving them the opportunity to participate in the event with novel activities and booths to be included in the Exhibition Hall. Activities should be interactive, making use of a variety of tools (experiments, videos, audio, games, simulations, quizes, mobile applications, use of scientific equipment, painting, crafts, etc.) to communicate the main messages, providing the public with the opportunity to participate actively. In addition, activities specifically targeting young children and students are encouraged. The main theme of the event is the transition to the digital and green age, inspired by the European Green Deal and the European Digital Strategy. Therefore, interested entities are encouraged to include elements in their activities which aim at raising awareness regarding the digital and green transition. In order to participate in the event, interested entities are requested to submit their Expression of Interest through an online form by Friday, June 4^th, 2021. More information regarding the European Researchers’ Night and the theme of this year’s event can be found on the RIF website. Any questions regarding the Call for Expressions of Interest can be submitted to the RIF Partner Support Centre by phone (22205000) or e-mail (support@research.org.cy). The event is organized in the framework of the EU funded Project ENGAGE, Grant Agreement No. 101036068, which is co-funded by the EU’s Horizon 2020 Programme for Research and Innovation. Ιn case of increased cases of COVID-19 in Cyprus in September, the event will be organized in a fully digital format.