Proposals under this topic should:

• Demonstrate cost-effective, sustainable and resource-efficient large scale production processes for obtaining one or more bio-based dedicated platform chemicals. Both upstream and downstream process aspects are in scope. The overall objective should target improving process efficiency, lowering CAPEX/OPEX, lowering the E-factor (process waste) and improving process safety. Enabling process technologies in scope include chemical, physicochemical, biotech or hybrid technologies, as well as process intensification and symbiosis concepts, if applicable to attain improvements in resource efficiency and sustainability performance.
• Indicate clearly the targeted feedstock(s), including availability and process flexibility aspects in relation to feedstock composition, if relevant. The cascading valorisation of secondary biomass and residual streams is also in scope.
• Validate (end TRL: 5 and above) the further conversion and integration of produced chemicals into final products. The chosen bio-based chemical(s) should be validated in market-relevant application(s).
• Include a task to integrate assessment based on the safe-and-sustainable-by-design (SSbD) framework, developed by the European Commission, for assessing the safety and sustainability of chemicals and materials. Under this context, projects are expected to contribute with and develop recommendations that can advance further the application of the SSbD framework.

Proposals should implement the multi-actor approach (MAA) and ensure adequate involvement of all key actors in the value chains relevant for this topic and across the sustainable circular bio-based system, including B2B end-users and feedstock providers.