Improved prediction, detection, and treatment approaches for comprehensive stroke management

Closed

Programme Category

EU Competitive Programmes

Programme Name

Innovative Health Initiative

Programme Description

IHI JU is based on the idea that interdisciplinary and cross-sector collaboration will enable perspective and breakthrough innovations in healthcare, including the pharmaceutical industry but also new fields such as biopharmaceuticals, medical technologies and biotechnologies.

Programme Details

Identifier Code

HORIZON-JU-IHI-2023-05-03

Call

Improved prediction, detection, and treatment approaches for comprehensive stroke management

Summary

Stroke is a preventable, treatable, and manageable disease and thus the potential to reduce its burden and its long-term consequences exists.

The challenge in stroke management is the lack of efficient and comprehensive pathways along the whole continuum of the disease – including the variation of structural settings depending on the location of the patient (rural vs. central) and between countries. The implementation of connected healthcare pathways will lead to an improvement in the outcome for the patients and thereby drive efficiency and effectiveness from a clinical and health resource perspective.

Integrating data is key to allow for modelling, artificial intelligence (AI) and machine learning (ML)-based evaluation to identify groups and individual persons at risk and assure early recognition of stroke, thereby providing faster diagnosis and optimal, patient-specific treatment, resulting in better outcomes for patients. Moreover, comprehensive stroke management continues in the post-acute treatment setting and includes long-term follow-up for secondary prevention and rehabilitation.

Innovative solutions for faster acquisition, integration, and better retention of multiple types of data and better organisation among the various actors across the entire stroke pathway are crucial to achieve optimal prevention and treatment focused on the needs of patients. Use of novel technologies for federated data analytics and interpretation could help in this direction and assist in providing the right treatment to patients in a timely manner, improving their outcomes.

Detailed Call Description

Applicants to this topic should address all the aims below in their proposals.

  • Develop approaches to integrate patient-relevant health data, from primary care / outpatient clinic, hospital, and rehabilitation settings, as relevant, improving data retention along the care pathway. Applicants could consider starting with a focus on patients at higher risk with the possibility to expand to other patients.
  • Develop a next generation of systems that promote interoperability of data from different settings (including intensive and acute care units) and support better clinical decision making. Strategic approaches for integration with the EHDS and community-based, collaborative integrated care should be considered.
  • Create solutions to foster better access to data for all involved healthcare professionals (primary care, hospital care and after hospital release e.g., rehabilitation) and support exchange of knowledge and information between the different actors – including at the level of algorithms and datasets that can be exchanged under ethically and legally sound conditions.
  • Develop innovative tools and approaches, for example ‘virtual human twin’ model approaches and AI/ML for enhanced computational modelling, optimised for transparency to users and non-users, federated data analytics, and visualisation for enhanced output/results view and interpretation. These tools aim at appropriate risk stratification, timely prediction of stroke and stroke recurrence, faster diagnosis, and treatment.
  • Propose innovative approaches to improve and expedite diagnostic and treatment decisions for streamlining operations and guiding patients in the continuum of stroke care in a patient-centric way. This should include consideration of the complexity of the organisational dimension.
  • Propose approaches to improve implementation and scale-up of treatment in Europe relying on multimodal clinical data capture and their better interpretation and use in patient management and clinical decision-making. This should include consideration of the regional differences in stroke management and access to treatment options across Europe.
  • Propose approaches to enhance precision of care delivery as well as improving patient experience and quality of life using new technologies, tools, and educational means (e.g., education on identification of risk factors, signs of stroke, treatment adherence).

Call Total Budget

€40 000 000

Financing percentage by EU or other bodies / Level of Subsidy or Loan

Expected IHI contribution per project: €10 000 000 – €13 000 000

Thematic Categories

  • Health
  • Industry
  • Research, Technological Development and Innovation

Eligibility for Participation

  • Large Enterprises
  • Other Beneficiaries
  • Private Bodies
  • Researchers/Research Centers/Institutions
  • State-owned Enterprises

Eligibility For Participation Notes

For all the above topics applicant consortia should ensure that at least 45% of the action’s eligible costs and costs for action-related additional activities are provided by in-kind contributions to operational activities (IKOP), financial contributions (FC), or in-kind contributions to additional activities (IKAA) from private members and/or contributing partners and the constituent or affiliated entities of the private members and/or of the contributing partners. Contributing partners may not contribute IKAA.

Applicants should propose a project duration such that it matches project activities and expected outcomes and impacts.

Call Opening Date

27/07/2023

Call Closing Date

16/01/2024

EU Contact Point

All questions regarding JU JU invitations should be directed to infodesk@ihi.europa.eu.