Programme Category
Programme Name
Programme Description
Horizon Europe is the European Union (EU) funding programme for the period 2021 – 2027, which targets the sectors of research and innovation. The programme’s budget is around € 95.5 billion, of which € 5.4 billion is from NextGenerationEU to stimulate recovery and strengthen the EU’s resilience in the future, and € 4.5 billion is additional aid.
Identifier Code
Call
Summary
While cancer research and innovation have generated novel treatment options, cancer patients across Europe need access to minimally-invasive, patient-centred diagnostic interventions which keep up with increasing demand in a complex and fragmented oncology healthcare landscape with increasing healthcare costs.
Pragmatic clinical trials focus on choosing between care options. Pragmatic trials evaluate effectiveness, the effect of diagnostics in routine (real-world) clinical practice.
Detailed Call Description
Proposals should address all of the following:
- Design and conduct randomised or cluster-randomised academic investigator-initiated pragmatic clinical trials to deliver effective and evidence-based diagnostic interventions for implementation by healthcare systems at the level of local communities, European regions, Member States and Associated Countries, taking into account stratification, such as biology, molecular features, sex, gender, cancer stage, and age. Clinical trial design and conduct could be aided by computational, simulation and visualisation tools and technologies where appropriate.
- The chosen diagnostic intervention(s) should be adapted to the particular needs of the target population and to the specificities of the provision of care at local, regional, or national level, duly reflecting the diversity across Member States and Associated Countries. Furthermore, affordability and accessibility should be taken into account.
- The successful proposals should clearly justify and describe the evidence supporting the chosen diagnostic intervention.
- The primary and secondary endpoints of the pragmatic clinical trial should support overall survival, patient-reported outcomes and quality of life issues considered important by and for cancer patients and their caregivers.
- Such endpoints should be defined together with patients and their caregivers through research that uses open knowledge, (social) innovation systems and support end-user engagement, such as living labs or other participative research models.
- Successful pragmatic clinical trials, including their analyses, should be completed within 5 years from the start of the project. Translational research is not within the scope of this topic.
- In all instances, sex- and gender-related issues must be taken into account. All data should be disaggregated by sex, gender, age and other relevant variables, such as by measures of socio-economic status or ethnicity.
Call Total Budget
Financing percentage by EU or other bodies / Level of Subsidy or Loan
100%
EU Contribution per project: between €6,00 and €8,00 million
Thematic Categories
- Education and training
- Health
- Research, Technological Development and Innovation
Eligibility for Participation
- Associations
- Educational Institutions
- International Organisations
- Local Authority clusters
- Natual person / Citizen / Individual
- NGOs
- Non Profit Organisations
- Other Beneficiaries
- Private Bodies
- Researchers/Research Centers/Institutions
- Semi-governmental organisations
- Small and Medium Enterprises (SMEs)
- State-owned Enterprises
Eligibility For Participation Notes
These pragmatic clinical trials should include stakeholders such as:
- physicians,
- academia,
- patients and their caregivers,
- patient representatives,
- SMEs,
- insurance companies,
- charities and foundations,
- research organisations, regional and national research, innovation
- civil society,
- health authorities.
Call Opening Date
Call Closing Date
National Contact Point(s)
Research and Innovation Foundation
29a Andrea Michalakopoulou, 1075 Nicosia
P.B. 23422, 1683 Nicosia
Telephone: +357 22205000
Fax: +357 22205001
Email: support@research.org.cy
Contact Person:
George Christou
Scientific Officer
gchristou@research.org.cy
(Publish Date: 10/02/2023-for internal use only)