Leveraging long-term field experiments and other datasets to develop AI-ready decision support systems for sustainable soil management

Opened

Code: 39379 | Identifier Code: HORIZON-MISS-2026-05-SOIL-04 | Programme name: 2939 | Sub-program: Missions | Start submission calls: 04/02/2026 | End submission calls: 23/09/2026

Long-term field experiments (LTEs) can be defined as “agricultural experiments for monitoring soil and crop properties under changing climate conditions and different management with a minimum duration of 20 years”. LTEs are typically owned or managed by public research institutions.

Enabling user-centred and open innovation initiatives to enhance soil health in Ukraine

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Code: 39376 | Identifier Code: HORIZON-MISS-2026-05-SOIL-03 | Programme name: 2939 | Sub-program: Missions | Start submission calls: 04/02/2026 | End submission calls: 23/09/2026

In Ukraine, soils are exposed to degradation due to nutrient mismanagement, acidification, erosion, compaction, salinisation, and contamination, with the war further contributing to devastation by releasing toxic elements, causing long-term damage to both ecosystems and human health

During military activities, soils are among the most heavily affected components of the environment, undergoing mechanical, chemical, and physical degradationThe war has also disrupted research and innovation activities, which further hinder the country’s ability to address soil degradation issues.

Particularly, as before the war, the innovation landscape in Ukraine was already in a need for more supportive political, regulatory and legislative frameworks, and more developed and improved innovation.

Antimicrobial resistance and antibiotic biosynthesis in soils: developing key understanding and counteractive strategies using a One-Health approach

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Code: 39373 | Identifier Code: HORIZON-MISS-2026-05-SOIL-02 | Programme name: 2939 | Sub-program: Missions | Start submission calls: 04/02/2026 | End submission calls: 23/09/2026

Soil biodiversity plays a major role in human, animal and ecosystem health. Soil microorganisms (bacteria and fungi) have been crucial in the discovery of antibiotics used in human and veterinary medicine.

However, soils can also be a hotspot for antimicrobial resistance development and can play a key role in the transfer of antimicrobial resistance genes between organisms and environmental compartments.

Antibiotic use is expected to increase globally due to the rising demand for food-producing animals, which may further exacerbate the development of antimicrobial resistance in soils.

According to the World Health Organization, antimicrobial resistance is one of the greatest threats to public health.

The driving forces for antimicrobial resistance development in soils are however understudied, as well as the role of soils in the exposure of humans and animals to antimicrobial resistance determinants. Moreover, our knowledge of antibiotics-related genes is currently limited, making it challenging to identify new compounds of interest. To better understand and combat antimicrobial resistance development in soils, a One-Health approach is needed.

Monitoring soil health in practice: equipping stakeholders to sample, analyse, and interpret soil health indicators

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Code: 39370 | Identifier Code: HORIZON-MISS-2026-05-SOIL-01 | Programme name: 2939 | Sub-program: Missions | Start submission calls: 04/02/2026 | End submission calls: 23/09/2026

Soil health assessments will be key in the EU, especially with initiatives like the upcoming Soil Monitoring and Resilience Directive. Assessments will provide critical data to support adaptive management practices that optimise soil health enhancing competitiveness and resilience.

Innovation for regional rail services and new guided transport systems

Opened

Code: 39367 | Identifier Code: HORIZON-JU-ER-2026-FA6FA7-01 | Programme name: 24432 | Start submission calls: 04/02/2026 | End submission calls: 07/05/2026

Regional railways are essential as a link to other transport services but also to serve Europe’s regions, its citizen and businesses, which is why their long-term viability should be ensured. To this end, total costs of ownership are to be reduced while maintaining high service quality and operational safety. The concept to be developed will be tailored to the regional railways and will include digitalisation, automation, and the use of new and mainstream technologies.

Safety and certification guidelines and demonstration of safety components for hyperloop

Opened

Code: 39364 | Identifier Code: HORIZON-JU-ER-2026-FA7-01 | Programme name: 24432 | Start submission calls: 04/02/2026 | End submission calls: 07/05/2026

EU-Rail promote forward looking activities, tackling disruptive technologies and thinking, performing exploratory research to accelerate the pace towards radical system innovations in the guided transport modes and supporting the evolution of the Innovation Programme in scope and targets.

Boosting innovation for better assessment of the added value of innovative integrated healthcare solutions

Opened

Code: 39358 | Identifier Code: HORIZON-JU-IHI-2026-12-SINGLE-STAGE-05 | Programme name: 23667 | Start submission calls: 15/01/2026 | End submission calls: 21/04/2026

With a view to harnessing new science and technologies, this topic aims to fund pre-competitive research and innovation for novel tools, methods, technologies that will foster the development of health innovations to prevent, intercept, diagnose, treat, and manage diseases and enable recovery more efficiently.

Boosting innovation through exploitation of digitalisation and data exchange in healthcare

Opened

Code: 39355 | Identifier Code: HORIZON-JU-IHI-2026-12-SINGLE-STAGE-04 | Programme name: 23667 | Start submission calls: 15/01/2026 | End submission calls: 21/04/2026

With a view to harnessing new science and technologies, this topic aims to fund pre-competitive research and innovation for novel tools, methods, technologies that will foster the development of health innovations to prevent, intercept, diagnose, treat and manage diseases and enable recovery more efficiently.

Boosting innovation for people-centred integrated healthcare solutions

Opened

Code: 39351 | Identifier Code: HORIZON-JU-IHI-2026-12-SINGLE-STAGE-03 | Programme name: 23667 | Start submission calls: 15/01/2026 | End submission calls: 21/04/2026

With a view to harnessing new science and technologies, this topic aims to fund pre-competitive research and innovation for novel tools, methods, technologies that will foster the development of health innovations to prevent, intercept, diagnose, treat and manage diseases, and enable recovery more efficiently.

Boosting innovation through better integration of fragmented health R&I efforts

Opened

Code: 39348 | Identifier Code: HORIZON-JU-IHI-2026-12-SINGLE-STAGE-02 | Programme name: 23667 | Start submission calls: 15/01/2026 | End submission calls: 12/04/2026

With a view to harnessing new science and technologies, this topic aims to fund pre-competitive research and innovation for novel tools, methods, technologies that will foster the development of health innovations to prevent, intercept, diagnose, treat, and manage diseases and enable recovery more efficiently.

Boosting innovation for a better understanding of the determinants of health

Opened

Code: 39344 | Identifier Code: HORIZON-JU-IHI-2026-12-SINGLE-STAGE-01 | Programme name: 23667 | Start submission calls: 15/01/2026 | End submission calls: 21/04/2026

With a view to harnessing new science and technologies, this topic aims to fund pre-competitive research and innovation for novel tools, methods and technologies that will foster the development of health innovations to prevent, intercept, diagnose, treat, and manage diseases and enable recovery more efficiently.

Accordingly, applicants must assemble a collaborative public-private partnership consortium reflecting the integrative and cross-sectoral nature of IHI JU, that is capable of addressing the challenge(s) and scope of the IHI JU Specific Objective 1 ‘contribute towards a better understanding of the determinants of health and priority disease areas’, as defined in IHI JU’s legal basis and described in more detail in the IHI JU SRIA.

Cross-border renewable energy works projects

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Code: 39341 | Identifier Code: CEF-E-2026-CBRENEW-WORKS | Programme name: 3569 | Sub-program: Connecting Europe Facility – Energy Infrastructure | Start submission calls: 05/02/2026 | End submission calls: 12/03/2026

This topic refers to works projects contributing to the implementation of a CB RES project. Works in the meaning of CEF Energy include the purchase, supply and deployment of components, systems and services including software, the development, construction and installation activities relating to a CB RES project, the acceptance of installations and the launching of a CB RES project.

Cross-border renewable energy studies projects

Opened

Code: 39337 | Identifier Code: CEF-E-2026-CBRENEW-STUDIES | Programme name: 3569 | Sub-program: Connecting Europe Facility – Energy Infrastructure | Start submission calls: 05/02/2026 | End submission calls: 12/03/2026

This topic refers to projects for studies contributing to the implementation of a CB RES project. Studies in the meaning of CEF Energy include activities needed to prepare cross-border RES project implementation, such as preparatory, mapping, feasibility, evaluation, testing and validation studies, including in the form of software, and any other technical support measure, including prior action to define and develop a cross-border RES project and decide on its financing, such as exploration of the sites concerned and preparation of the financial package.

Global collaboration action on climate and health in sub-Saharan Africa

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Code: 39334 | Identifier Code: HORIZON-JU-GH-EDCTP3-2026-02-CH-01-two-stage | Programme name: 29117 | Start submission calls: 14/01/2026 | End submission calls: 04/03/2026

Proposals under this topic should include:

A/ Minimum one of the following:

1. Conduct a phase IIb or III clinical trial, or post-authorisation effectiveness (phase IV) trial developing a preventive or therapeutic medicine, or vaccine against the pathogens in scope, OR
2. Conduct large-scale implementation research on a validated (corresponding to Technology Readiness Level 8) medical device or novel vector control intervention for pathogens in scope in the context of integrated disease control interventions (which may include surveillance systems, early warning tools, diagnostics, and vector control innovations).

B/ In addition, proposals should address ALL of the following:

1. Where appropriate, integrate the OneHealth aspect in the research, the cross-over between human health with environmental and animal health (guidelines EU for OneHealth incorporation in climate and health). Package interventions could also be considered here.
2. Encompass primary health care systems, community health workers and the community into the study.
3. Include underserved and vulnerable populations such as children under five, pregnant women, elderly people, people with co-morbidities, immunocompromised people, and displaced populations including those living in informal settlements in urban or peri-urban areas as relevant.

C/ In addition, the proposals should address at least two of the following:

1. Include indigenous populations as defined per national/regional context.
2. Study the impact of climate change on supply chains and access to medical countermeasures.
3. Involve local, regional or national health and climate authorities/policymakers, bridging the gap between research and policymaking.
4. Integrate research in national adaptation plans and National Health Emergency Plans.
5. Include adaptations of primary health care systems to climate change, for example infrastructural improvements or the training of the primary care workforce.

Global collaboration action towards better prevention, treatment and clinical management of HIV co-infections or co-morbidities in sub-Saharan Africa

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Code: 39332 | Identifier Code: HORIZON-JU-GH-EDCTP3-2026-01-HIV-03-two-stage | Programme name: 29117 | Start submission calls: 14/01/2026 | End submission calls: 04/03/2026

The proposals submitted under this topic should generate evidence on efficacy, immunogenicity, safety and/or clinical utility for healthcare professionals and clinicians in SSA of novel/improved products that aim to improve prevention and/or treatment outcomes for a co-infection or co-morbidity to HIV.

This includes the prevention of developing HIV co-morbidities or advanced HIV disease (as per WHO definition^[4]). Proposals should address effective service integration in different healthcare systems in SSA, including safer polypharmacy use.

The proposals submitted under this topic should address late-stage (phase IIb and thereafter) clinical development.

Global collaboration action for prevention and treatment of Lower Respiratory Tract Infections (LRTIs) in sub-Saharan Africa

Opened

Code: 39329 | Identifier Code: HORIZON-JU-GH-EDCTP3-2026-01-LRTI-02-two-stage | Programme name: 29117 | Start submission calls: 14/01/2026 | End submission calls: 04/03/2026

Proposals submitted under this topic should carry out late-stage clinical studies (Phase IIb and after) advancing prevention and treatment of pathogens related to Lower respiratory tract infection (LRTI) by evaluating the safety, immunogenicity, efficacy and/or effectiveness of approved or novel preventive or therapeutic candidates targeting individuals in SSA.

Global collaboration action for the development of TB drugs for therapy and chemoprophylaxis in adults and children in sub-Saharan Africa

Opened

Code: 39325 | Identifier Code: HORIZON-JU-GH-EDCTP3-2026-01-TB-01-two-stage | Programme name: 29117 | Start submission calls: 14/01/2026 | End submission calls: 04/03/2026

Proposals submitted under this topic should address the following points:

• Advance the clinical development by generating clinical data (Phase IIa trials and beyond) to progress towards registration of new TB drugs, improved or shorter therapeutics TB regimens, chemoprophylaxis and/or more comprehensive interventions combining therapeutics and chemoprophylaxis.

In addition, proposals submitted under this topic are also encouraged to:

• Generate clinical data with a focus on priority populations, including women of childbearing potential and pregnant women, and particularly children, especially for assets in late-stage development.
• Generate clinical data progressing development of new or improved treatment regimens for MDR-TB and XDR-TB.

AGRIP-MULTI-2026-IM-FRESH-FV

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Code: 39321 | Identifier Code: AGRIP-MULTI-2026-IM-FRESH-FV | Programme name: 18076 | Start submission calls: 22/01/2026 | End submission calls: 23/04/2026

The Commission is committed to promoting balanced and healthy dietary practices. Actions shall highlight the benefits of consuming fresh fruit and vegetables in a balanced diet.

The messages could notably focus on aiming at having at least five portions of a variety of fruit and vegetables each day; knowing the place of fruit and vegetables in the food pyramid and understanding the beneficial impact of fruit and vegetable consumption on health.

AGRIP-MULTI-2026-TC-ORG-SUST

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Code: 39318 | Identifier Code: AGRIP-MULTI-2026-TC-ORG-SUST | Programme name: 18076 | Start submission calls: 22/01/2026 | End submission calls: 23/04/2026

• The objective is to increase the awareness and recognition of the Union quality scheme on organic production.

Information and promotion programmes on the Union quality scheme on organic production method should be a key priority since this scheme provides consumers with assurances on the sustainability, quality and characteristics of the product and the production process used and the environmental benefits they generate, thereby achieving added value for the products concerned and enhancing their market opportunities.

• The objective is to highlight the sustainability of Union agriculture, stressing its beneficial role for the climate, the environment and animal welfare. The production method(s) of the promoted product(s) shall cover at least two of the areas of actions listed in Article 31(4) of Regulation (EU) 2021/2115 while respecting the conditions laid down in paragraph 5 of that Article.

AGRIP-MULTI-2026-TC-ALL

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Code: 39315 | Identifier Code: AGRIP-MULTI-2026-TC-ALL | Programme name: 18076 | Start submission calls: 22/01/2026 | End submission calls: 23/04/2026

The objectives of these programmes shall comply with the general and specific objectives set out and the aims listed in Articles 2 and 3, respectively, of Regulation (EU) No 1144/2014.